The study examines at the influence of Strategic Human Resource Management (SHRM) on organizational resilience, focusing on the mediating roles of organizational culture, employee resilience, and self-efficacy, as well as the moderating effect of AI adoption. The data was statistically examined using Partial Least Squares Structural Equation Modelling, with 376 valid replies from diverse businesses. The findings show that SHRM has a beneficial influence on organizational resilience, with mediators enhancing the connection and AI adoption improving the effectiveness of strategic HR practices. This study combines HR practices, psychological factors, and technological capabilities to develop a framework for understanding resilience, as well as practical insights for implementing strategic HR policies and AI technologies to enhance organizational resilience and sustainability.